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What is the difference between stable and unstable angina in coronary artery disease?
What is the difference between stable and unstable angina in coronary artery disease?-February 2024
Feb 15, 2026 7:56 AM

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Stable vs. Unstable Angina in Coronary Artery Disease

Coronary artery disease (CAD) is a condition characterized by the narrowing or blockage of the coronary arteries, which supply oxygen-rich blood to the heart muscle. Angina, a common symptom of CAD, refers to chest pain or discomfort that occurs when the heart muscle does not receive enough blood and oxygen.

Stable Angina

Stable angina is a predictable and relatively consistent pattern of chest pain that occurs during physical exertion or emotional stress. It is usually caused by a partial blockage in one or more of the coronary arteries, restricting blood flow to the heart. The pain experienced in stable angina is typically described as a squeezing or pressure-like sensation in the chest, which may radiate to the left arm, shoulder, jaw, or back. The pain usually subsides with rest or the use of medications, such as nitroglycerin.

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Stable angina is considered stable because the symptoms occur in a consistent manner and are relatively predictable. The pain is usually reproducible and can be triggered by specific activities or situations. The underlying blockage in the coronary artery causing stable angina is often stable and does not progress rapidly.

Unstable Angina

Unstable angina, on the other hand, is a more serious and potentially life-threatening condition. It is characterized by chest pain that occurs at rest or with minimal exertion, and the pain may be more severe and prolonged compared to stable angina. Unstable angina is typically caused by the rupture of a vulnerable plaque within the coronary artery, leading to the formation of a blood clot that partially or completely blocks the artery. This sudden and severe reduction in blood flow to the heart can result in a heart attack or myocardial infarction.

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Unlike stable angina, unstable angina is unpredictable and does not follow a consistent pattern. The pain may occur at any time, even during periods of rest or sleep. It may also be accompanied by other symptoms such as shortness of breath, nausea, lightheadedness, or profuse sweating. Unstable angina requires immediate medical attention as it is a sign of an acute coronary syndrome and indicates an increased risk of a heart attack.

Conclusion

In summary, stable angina is characterized by predictable chest pain that occurs during physical exertion or stress, while unstable angina is more severe, unpredictable, and can occur at rest. Stable angina is caused by a partial blockage in the coronary artery, whereas unstable angina is often the result of a vulnerable plaque rupture and subsequent blood clot formation. Understanding the differences between stable and unstable angina is crucial in the diagnosis and management of coronary artery disease.

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Keywords: angina, stable, unstable, coronary, artery, blockage, occurs, disease, characterized

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