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What are the symptoms of hyperparathyroidism?
What are the symptoms of hyperparathyroidism?-February 2024
Feb 26, 2026 2:15 AM

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Definition: What are the symptoms of hyperparathyroidism?

Hyperparathyroidism is a medical condition characterized by the overactivity of the parathyroid glands, which are responsible for regulating calcium levels in the body. When these glands produce excessive amounts of parathyroid hormone (PTH), it can lead to various symptoms and complications.

Primary Hyperparathyroidism Symptoms

Primary hyperparathyroidism is the most common form of the condition and is typically caused by a benign tumor in one or more of the parathyroid glands. The symptoms of primary hyperparathyroidism may include:

1. Bone pain: Excessive levels of PTH can cause bone pain, especially in the bones of the arms, legs, and spine. This pain may be described as a dull ache or tenderness.

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2. Kidney stones: Increased calcium levels in the blood can lead to the formation of kidney stones. These stones can cause severe pain in the lower back or abdomen, along with symptoms like blood in the urine and frequent urination.

3. Fatigue and weakness: Hyperparathyroidism can cause fatigue, weakness, and a general feeling of tiredness. This can be attributed to the disruption of calcium balance in the body.

4. Digestive issues: Some individuals with hyperparathyroidism may experience symptoms such as nausea, vomiting, constipation, or loss of appetite.

5. Frequent urination: Excessive calcium levels can lead to increased urine production, resulting in frequent urination.

6. Mental health changes: Hyperparathyroidism can affect mental well-being, leading to symptoms like depression, anxiety, and difficulty concentrating.

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Secondary Hyperparathyroidism Symptoms

Secondary hyperparathyroidism occurs as a result of another underlying condition, such as chronic kidney disease or vitamin D deficiency. The symptoms of secondary hyperparathyroidism may include:

1. Bone pain and fractures: Similar to primary hyperparathyroidism, secondary hyperparathyroidism can cause bone pain and increase the risk of fractures.

2. Muscle weakness: Elevated PTH levels can lead to muscle weakness and decreased muscle function.

3. Itching and skin changes: Some individuals with secondary hyperparathyroidism may experience itching, dry skin, or changes in skin pigmentation.

4. Cardiovascular complications: Secondary hyperparathyroidism can contribute to cardiovascular problems, including high blood pressure and an increased risk of heart disease.

5. Abnormal calcium and phosphorus levels: Secondary hyperparathyroidism can disrupt the balance of calcium and phosphorus in the body, leading to complications such as osteoporosis and soft tissue calcification.

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It is important to note that the symptoms of hyperparathyroidism can vary from person to person, and some individuals may not experience any noticeable symptoms. If you suspect you may have hyperparathyroidism, it is crucial to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.

Keywords: hyperparathyroidism, symptoms, secondary, calcium, levels, primary, weakness, condition, parathyroid

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