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Definition: How does telomerase activator help in maintaining telomere length?

Telomeres naturally shorten with each cell division, eventually leading to cellular senescence or apoptosis. However, the activation of telomerase can counteract this shortening process by adding repetitive DNA sequences to the telomeres, thus maintaining their length and integrity.

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Telomerase activators work by enhancing the expression or activity of telomerase in cells. They can either directly increase the production of telomerase or indirectly stimulate its activity. By doing so, telomerase activators help to prevent telomere shortening and delay the onset of cellular aging.

Maintaining telomere length is crucial for overall health and longevity. Shortened telomeres have been associated with various age-related diseases, including cardiovascular disease, cancer, and neurodegenerative disorders. By preserving telomere length, telomerase activators have the potential to promote healthy aging and extend lifespan.

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It is important to note that while telomerase activators show promise in maintaining telomere length, their long-term effects and potential risks are still being studied. Further research is needed to fully understand the mechanisms and optimize the use of telomerase activators for therapeutic purposes.

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