How do anti-inflammatory drugs reduce inflammation in the body?-February 2024-www.zdask.com

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Definition: How do anti-inflammatory drugs reduce inflammation in the body?

Anti-inflammatory drugs are medications that are used to reduce inflammation in the body. Inflammation is a natural response of the immune system to injury or infection, but it can also be caused by chronic conditions such as arthritis or autoimmune diseases.

There are several ways in which anti-inflammatory drugs work to reduce inflammation:

1. Inhibition of prostaglandin synthesis: Prostaglandins are hormone-like substances that play a key role in the inflammatory process. Anti-inflammatory drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs), work by inhibiting the synthesis of prostaglandins. This helps to reduce pain, swelling, and redness associated with inflammation.

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2. Suppression of immune response: Inflammation is often caused by an overactive immune response. Corticosteroids, a type of anti-inflammatory drug, work by suppressing the immune system. They reduce the production of inflammatory substances and decrease the activity of immune cells involved in the inflammatory process.

3. Inhibition of enzymes: Some anti-inflammatory drugs, such as selective COX-2 inhibitors, work by inhibiting specific enzymes involved in the production of inflammatory substances. By blocking these enzymes, these drugs help to reduce inflammation and pain.

4. Modulation of cytokines: Cytokines are proteins that regulate the immune response and play a role in inflammation. Certain anti-inflammatory drugs, such as biologic agents, work by targeting specific cytokines or their receptors. By modulating the activity of these cytokines, these drugs can help to reduce inflammation and improve symptoms.

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It is important to note that while anti-inflammatory drugs can be effective in reducing inflammation, they may also have side effects. Common side effects include stomach ulcers, gastrointestinal bleeding, and increased risk of cardiovascular events. It is important to use these medications under the guidance of a healthcare professional and to follow the recommended dosage and duration of treatment.

Keywords: inflammatory, inflammation, reduce, immune, response, cytokines, substances, enzymes, medications