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How do anti-inflammatory drugs interact with the body’s natural inflammatory response?
How do anti-inflammatory drugs interact with the body’s natural inflammatory response?-February 2024
Feb 12, 2026 5:23 PM

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Definition: How do anti-inflammatory drugs interact with the body’s natural inflammatory response?

Anti-inflammatory drugs are medications that are designed to reduce inflammation in the body. Inflammation is a natural response of the immune system to injury or infection, characterized by redness, swelling, pain, and heat in the affected area. While inflammation is a crucial part of the body’s defense mechanism, excessive or chronic inflammation can lead to tissue damage and various diseases.

Anti-inflammatory drugs work by interfering with the body’s natural inflammatory response. They can be classified into two main categories: nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids.

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Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

NSAIDs are commonly used to relieve pain, reduce inflammation, and lower fever. They work by inhibiting the production of prostaglandins, which are hormone-like substances that play a key role in the inflammatory process. Prostaglandins are produced by an enzyme called cyclooxygenase (COX), and NSAIDs block the action of this enzyme, thereby reducing the production of prostaglandins.

By reducing prostaglandin levels, NSAIDs help to alleviate pain and swelling associated with inflammation. However, it’s important to note that NSAIDs primarily target the symptoms of inflammation rather than addressing the underlying cause.

Corticosteroids

Corticosteroids, also known as steroids, are synthetic drugs that mimic the effects of hormones naturally produced by the adrenal glands. They have potent anti-inflammatory properties and are often used to treat various inflammatory conditions, such as arthritis, asthma, and skin disorders.

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Corticosteroids work by suppressing the immune system and reducing the production of inflammatory substances, such as cytokines and chemokines. They also inhibit the activity of immune cells involved in the inflammatory response, such as neutrophils and macrophages.

Unlike NSAIDs, corticosteroids can target both the symptoms and the underlying cause of inflammation. However, they are generally prescribed for short-term use due to their potential side effects when used for extended periods.

In conclusion, anti-inflammatory drugs interact with the body’s natural inflammatory response by reducing the production of inflammatory substances, inhibiting the activity of immune cells, and alleviating the symptoms associated with inflammation. They play a crucial role in managing various inflammatory conditions and promoting overall health and well-being.

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Keywords: inflammatory, inflammation, nsaids, response, corticosteroids, natural, immune, production, reducing

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