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How can exercise affect SHBG levels in older adults?
How can exercise affect SHBG levels in older adults?-February 2024
Feb 13, 2026 4:23 AM

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How can exercise affect SHBG levels in older adults?

Sex hormone-binding globulin (SHBG) is a protein that binds to sex hormones, such as testosterone and estrogen, in the bloodstream. It plays a crucial role in regulating the availability and activity of these hormones in the body.

As individuals age, their SHBG levels tend to increase. This can lead to a decrease in the free, or unbound, levels of sex hormones, which may have various implications for overall health and well-being.

Exercise and SHBG Levels

Regular exercise has been shown to have a positive impact on SHBG levels in older adults. Several studies have demonstrated that engaging in physical activity can help reduce SHBG levels, thereby increasing the availability of sex hormones in the body.

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One possible mechanism through which exercise affects SHBG levels is by promoting weight loss and reducing body fat percentage. Adipose tissue, or fat cells, produce SHBG, and higher levels of body fat have been associated with increased SHBG production. By engaging in regular exercise, individuals can decrease their body fat percentage, leading to a decrease in SHBG production.

Additionally, exercise has been shown to improve insulin sensitivity and reduce insulin resistance. Insulin resistance has been linked to higher SHBG levels, and by improving insulin sensitivity, exercise can help lower SHBG levels in older adults.

Benefits of Modulating SHBG Levels

Modulating SHBG levels through exercise can have several potential benefits for older adults:

  • Improved hormone balance: By increasing the availability of sex hormones, exercise can help maintain a healthier hormone balance, which may have positive effects on various aspects of health, including bone density, muscle mass, and cognitive function.
  • Enhanced sexual health: Higher levels of sex hormones can contribute to improved sexual function and libido in older adults.
  • Reduced risk of chronic diseases: Maintaining optimal hormone levels through exercise may help reduce the risk of chronic diseases, such as osteoporosis, cardiovascular disease, and metabolic disorders.
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Conclusion

Regular exercise can play a significant role in modulating SHBG levels in older adults. By reducing SHBG production and increasing the availability of sex hormones, exercise can have numerous benefits for overall health and well-being. It is important for older adults to engage in a well-rounded exercise routine that includes both cardiovascular and strength training exercises to optimize the effects on SHBG levels.

Keywords: levels, exercise, adults, hormones, hormone, availability, health, insulin, decrease

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