Foxs midseason lineup will look substantially different from its fall schedule.

The network revealed its midseason premiere dates, and while there are a few carryovers from the fallDoc anchoring Tuesday nights, animation on Sundays (though that lineup is shuffling as well) and a Gordon Ramsay show on Thursdays the schedule will feature different programming in about half of its 15 weekly primetime hours.

The slate includes the return of American Dad! to Fox, where it began its life before moving to TBS for more than a decade. The animated show from Seth MacFarlane will premiere Feb. 22, where it will join Family Guy (which debuts a week earlier) and the ongoing Universal Basic Guys. The Simpsons will conclude its 37th season on Feb. 15, with the shows milestone 800th episode in its usual 8 p.m. spot and the season finale at 8:30. Foxs four-season pickup of the series earlier this year included shortening those seasons to 15 episodes each; the previous two had 18 episodes, and for most of The Simpsons life a season meant 20 or more. Family Guy will move to the 8 p.m. spot on Feb. 22 and get double runs at 8 and 9:30 for four weeks, before the previously announced Biblical miniseries The Faithful premieres March 22.

The Masked Singer will have a two-hour premiere on Jan. 7, then scale back to its usual hour-long format the following week. The Johnny Knoxville-hosted Fear Factor: House of Fear will pair with it starting Jan. 14.

On the scripted side, Best Medicine an adaptation of the British series Doc Martin that stars Josh Charles will premiere on Jan. 6 and pair with Doc on Tuesdays. Memory of a Killer, starring Patrick Dempsey, debuts Jan. 26 following the survival competition Extracted. Live-action comedies Animal Control and Going Dutch are set for Jan. 15 and will follow the final two episodes of Hells Kitchen and Next Level Chef (which debuts Jan. 29) on Thursday nights.

Foxs midseason dates are below. All times are ET/PT.

Tuesday, Jan. 6

8 p.m.: Best Medicine

Wednesday, Jan. 7

8 p.m.: The Masked Singer

Wednesday, Jan. 14

9 p.m.: Fear Factor: House of Fear

Thursday, Jan. 15

9 p.m.: Animal Control

9:30 p.m.: Going Dutch

Monday, Jan. 26

8 p.m.: Extracted

9 p.m.: Memory of a Killer

Thursday, Jan. 29

8 p.m.: Next Level Chef

Sunday, Feb. 15

8 p.m.: The Simpsons (800th episode)

8:30 p.m.: The Simpsons (season finale)

9 p.m.: Universal Basic Guys

9:30 p.m.: Family Guy

Sunday, Feb. 22

8 p.m.: Family Guy

8:30 p.m.: Universal Basic Guys

9 p.m.: American Dad!

9:30 p.m.: Family Guy

Sunday, March 22

8 p.m.: The Faithful